Plain-English translation of NCT05589688 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
Researchers want to understand how — an antiviral medication used to treat herpes and chickenpox infections — works in people with obesity. Right now, doctors aren't sure how to safely dose this medication for patients who are overweight or have obesity, so this study will help fill that gap by measuring how the body processes a single dose in different body types.
Currently, doctors don't have enough information about how this medication behaves in people with obesity, which makes it hard to know whether standard doses are safe and effective for these patients. This research will help doctors prescribe the right dose based on a person's weight and body type.
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You would receive a single dose of the medication through an IV line over one hour at a hospital research center. Researchers would then collect blood samples over several hours or days to measure how your body processes the medication. You would be assigned to one of four groups based on your BMI (normal weight, overweight, or obesity), so researchers can compare how different body types handle the same dose.
AI-generated summary from trial data · Jun 8, 2026 · Not medical advice
France