Plain-English translation of NCT05599061 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Coronary Artery Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
After surviving a major heart attack, many patients have blockages in multiple heart arteries. This trial is testing whether placing a stent (a small metal tube) in a secondary blockage that shows certain warning signs is better than treating patients with medication alone. Researchers will compare these two approaches over 4 years to see which helps patients live longer and healthier lives.
Doctors can now detect early warning signs in artery blockages using special imaging, but it's unclear whether treating these risky blockages with a stent actually improves outcomes or if medication alone is just as safe and effective. This trial aims to answer that important question.
You likely qualify if…
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If you qualify, doctors will first use a special pressure wire and imaging test to confirm which blockages need treatment. You will then be randomly assigned to either receive a stent placement plus medication or medication alone. You will attend follow-up appointments and imaging visits for 4 years to monitor your heart health and see how well each approach works.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
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