Plain-English translation of NCT05601453 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study tracks patients who are receiving a second heart valve replacement using a minimally invasive catheter procedure (called redo-TAVI). As more people receive their first catheter-based heart valve, doctors need to better understand what happens when that valve stops working and patients need a second one — and which approach works best for different patients.
Right now, about 1–3% of patients who receive a catheter-based heart valve will eventually need a second one because the first valve fails or degenerates. There is limited information about how well this second procedure works and which valve design gives patients the best outcomes. As this treatment becomes more common in younger, healthier patients, the number of people needing re-treatment is expected to rise, making this research increasingly important.
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If you qualify, you would undergo a second catheter-based heart valve replacement procedure using the study valve. The research team would collect information about your procedure, your recovery, and your health at two follow-up visits — one at 30 days and another at 12 months after the procedure. Both follow-up visits would take place at the hospital, and your medical information would be added to a registry that helps doctors understand how well this second procedure works.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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