Plain-English translation of NCT05606536 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
During surgery, doctors give patients fluids through an IV to help their body get enough oxygen and stay stable. This study is testing whether giving different amounts of fluid at different speeds affects how well blood circulates to tissues after surgery and how diluted the blood becomes. Researchers want to understand which fluid rates work best for patient recovery.
Surgery can damage the delicate lining of blood vessels, which can affect how blood flows to tissues and cause the blood to become diluted. Doctors don't yet know the best way to give fluids during surgery to prevent these problems and help patients recover better.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will receive fluids during your surgery according to one of several different protocols—some with faster rates at the start and slower rates later, others with standard care. The researchers will monitor how your blood circulates and how diluted your blood becomes during and after the surgery. Your participation is integrated into your routine surgical care, with extra monitoring but no additional procedures beyond what your surgeon already planned.
AI-generated summary from trial data · Sep 24, 2026 · Not medical advice
Czechia
Sponsor
University Hospital Hradec Kralove
Enrollment target
~80 participants
Started
October 2022
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
David Astapenko, MD, PhD
University Hospital Hradec Kralove
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.