Plain-English translation of NCT05610735 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This study is testing whether adding (an extract from the plant) to liposomal doxorubicin—a chemotherapy drug given through an IV—might work better together for women with ovarian cancer that has come back after prior chemotherapy. The trial has two phases: first, researchers will test different doses of the supplement to find the safest and most tolerable amount; then, in the second phase, they'll test whether this combination helps shrink tumors and improve survival.
Current treatments for recurrent ovarian cancer have limited success, especially when the cancer has become resistant to platinum-based chemotherapy. Researchers hope that combining this traditional plant extract with standard chemotherapy might improve how well the treatment works and help more patients.
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You will take capsules of the plant supplement by mouth every day for up to two years. Every four weeks, you'll receive an intravenous infusion of the chemotherapy medication at a hospital or clinic, lasting about an hour. The study will monitor you closely with blood tests and imaging scans to see how you're responding and to watch for side effects. Depending on how well the treatment is working and any side effects you experience, your doctor may adjust your doses or continue treatment for up to 10 cycles of chemotherapy.
AI-generated summary from trial data · Jul 3, 2026 · Not medical advice
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