Take a weekly injection to help prevent bleeding episodes in hemophilia

Take a weekly injection to help prevent bleeding episodes in hemophilia | stella

What is this trial?

This trial is testing a new medication called to help prevent bleeding episodes in children with hemophilia A or B. is given as a weekly injection under the skin. Researchers want to see if this treatment works better than the standard care that participants have been receiving.

Children with hemophilia struggle with frequent, serious bleeding episodes that can be painful and dangerous. Current treatments either require frequent infusions or don't always prevent bleeds well, especially in patients who have developed inhibitors (resistance to standard factor replacement). This medication aims to offer a simpler, more effective way to prevent bleeds.

Do you qualify?

You likely qualify if…

you are a boy between 1 and 17 years old and meet the minimum weight requirement for your age group
you have been diagnosed with severe hemophilia A or moderate-to-severe hemophilia B (whether or not you have inhibitors)
you have at least one year of medical records or diary entries documenting all your factor infusions and bleeding episodes
if you don't have inhibitors, you have been on a stable, regular bleeding prevention treatment plan for at least 12 months before joining
if you do have inhibitors, you have been receiving on-demand bypass treatment and had at least 12 or more bleeding episodes in the past year (depending on your hemophilia type)

You likely don't qualify if…

you have a history of blood clots, heart disease, or certain genetic clotting disorders
you have a planned surgery scheduled during the study period
you have any bleeding disorder other than hemophilia A or B
you have abnormal results on recent blood tests, kidney tests, or liver tests
you have a serious medical or mental health condition that would make the study unsafe for you

What participation looks like

You would participate in this trial for about 14 months total: one month of screening and baseline visits, 12 months of receiving the medication, and one month of follow-up. During the 12-month treatment phase, you would receive a weekly injection of the medication, either at home or at the study clinic — whatever works best for you. The study team will track how many bleeding episodes you have and monitor your safety throughout.

AI-generated summary from trial data · Jun 3, 2026 · Not medical advice

Testing a New Bleeding Prevention Treatment for Children With Hemophilia

What is this trial?

Do you qualify?

What participation looks like

Trial locations(34 sites)