Plain-English translation of NCT05618626 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
This study doesn't follow the usual testing phases โ it may be an observational study or a different type of research.
This trial is testing whether a structured 12-month lifestyle program can help prevent serious liver and heart diseases in people with gallstones or a history of gallbladder removal. The program combines supervised exercise sessions (designed to build muscle and strength) with a special anti-inflammatory diet rich in fiber and legumes, along with better sleep habits and fasting periods. Researchers want to see if this approach can reduce your risk of developing fatty liver disease and cardiovascular problems, which people in your situation face at higher rates.
People who have gallstones or have had their gallbladder removed are at higher risk of developing nonalcoholic fatty liver disease and heart disease, especially men. Current standard care doesn't always prevent these complications, so this trial is testing whether a personalized, intensive lifestyle intervention can better protect your health.
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If you join, you'll be randomly assigned to either a control group (which receives standard health advice and education) or an intervention group (which receives the intensive program). The intervention group will participate in supervised exercise sessions at a local gym twice weekly for the first two months, then transition to once-weekly in-person sessions combined with home-based telehealth exercise for months 3โ6, followed by monthly phone check-ins. You'll also meet with nutritionists to follow the anti-inflammatory diet plan. Throughout the 12-month program and beyond, you'll have health evaluations (blood tests, ultrasounds, fitness assessments) at the beginning, at 12 months, and at 24 and 36 months to track your progress.
AI-generated summary from trial data ยท Jun 12, 2026 ยท Not medical advice
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