Plain-English translation of NCT05619588 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing the Exactech Vantage Total Ankle System, a surgical device designed to replace a damaged ankle joint. Researchers want to see how well this device works and how safe it is over a 10-year period after surgery. The study will follow nearly 370 people who receive this ankle replacement.
Severe ankle arthritis can make it very painful and difficult to walk or move. This trial exists to make sure the new device is truly safe and effective for people who need ankle replacement surgery, and to understand how long it lasts.
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You would have ankle replacement surgery using the Vantage device, then return for regular check-up visits over the next 10 years. During these visits, doctors will examine your ankle, ask you questions about how well it's working, and possibly take X-rays or other images. The study tracks how the device performs and whether any problems develop over time.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
United States
Enrollment target
~370 participants
Started
April 2017
Primary completion
December 2030
Age range
21 Years and older
Last updated on clinicaltrials.gov in February 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Rachael Craig
Duke Department of Orthopaedic Surgery
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.