Plain-English translation of NCT05640752 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing two different strategies for evaluating patients with stable chest pain to determine who truly needs advanced heart imaging. The study compares a European approach versus a British approach, both of which use your age, sex, symptoms, and risk factors to predict your heart disease risk. The goal is to find a smarter way to order imaging tests—catching those who need them while avoiding unnecessary scans for those who don't.
Many patients with chest pain receive heart imaging scans that turn out to be normal, which wastes resources and can cause unnecessary anxiety. This trial exists to find the best set of rules for deciding upfront who really needs imaging and who can safely be managed with medication alone.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to one of two groups, each using a different set of clinical guidelines to determine whether you need a heart imaging scan. A doctor will evaluate your risk factors (age, symptoms, blood pressure, cholesterol, smoking history, diabetes) using your assigned strategy. Depending on your risk score, you may be advised to have a heart imaging scan or to start heart-protective medications without imaging. You will be followed for one year to track your health outcomes and whether you had any heart-related problems.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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