Plain-English translation of NCT05643859 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is studying how dietary fiber supplements affect the bacteria that live in your colon. Researchers want to understand whether taking a daily fiber supplement can change the types and amounts of these bacteria in helpful ways. This could eventually lead to better ways to support gut health in people with certain rectal conditions.
The bacteria in your colon play an important role in digestive health, but researchers don't yet fully understand how fiber supplementation changes these bacterial communities. Learning this could help doctors recommend better dietary approaches to support patients with benign rectal problems.
You likely qualify if…
You likely don't qualify if…
You will take a daily fiber supplement by mouth for 28 days. During the study, you will have a colonoscopy, proctoscopy, or anoscopy procedure (standard care) where your doctor looks inside your colon or rectum and may take small tissue samples. You will also have blood samples collected at the start of the study and at a follow-up visit. The entire study lasts about one month.
AI-generated summary from trial data · Jul 21, 2026 · Not medical advice
United States