Plain-English translation of NCT05648175 on ClinicalTrials.gov ↗ · Source last updated · Translation generated ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether an artificial intelligence system can make treatment decisions as well as a team of healthcare professionals. You would receive online cognitive behavioral therapy (a proven talk therapy for depression) either way, but the study is comparing two different methods of deciding how much additional support you need—whether that comes from an AI system that analyzes your answers to questions and a depression screening test, or from doctors and therapists who review your symptoms and history.
Depression is common and serious, but many people don't get the right intensity of treatment they need. This study wants to know if an AI system could help match people to the best treatment level as effectively as experienced doctors can, which could eventually help more people get faster, more personalized care.
You likely qualify if…
You likely don't qualify if…
First, you'll have a secure video appointment with a research team member to confirm your depression diagnosis. Then you'll be randomly assigned to one of two groups—one where doctors decide your treatment plan, and one where an AI system decides it based on your answers to questions and a depression screening score. Either way, you'll receive online therapy, and you may also receive additional phone or video support with a therapist depending on which group you're in. The study team will keep track of how well the treatment works for you over time.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Canada