Testing a supplement to protect baby brains during pregnancy complications

This trial is testing whether melatonin, a naturally occurring hormone in the body, can help protect a baby's developing brain when pregnancy complications limit fetal growth. Researchers believe melatonin may reduce brain injury in babies by acting as a powerful protector against cell damage. Half of pregnant women in the study will receive melatonin, and half will receive a placebo (inactive pill), to see if this treatment can improve long-term brain health in newborns.

Babies with severe growth restriction due to placental problems often experience brain injury, and current treatments only help in the final hours before birth. This medication crosses the placenta easily and could potentially protect the baby's brain over weeks before delivery, filling an important gap in how doctors care for these high-risk pregnancies.