Plain-English translation of NCT05651724 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
GRIPonMASH is a large research study designed to identify people at high risk for fatty liver disease — a condition where fat builds up in the liver. Researchers will use simple blood tests and ultrasound scans to screen 10,000 people across 10 European countries who have diabetes, obesity, metabolic syndrome, or high blood pressure. The study will also collect blood samples and small tissue samples to better understand what causes this disease and find early warning signs.
Fatty liver disease is becoming more common in people with diabetes and obesity, but it's often detected too late. This study aims to find better, non-invasive ways to catch the disease early so doctors can help patients before serious liver damage occurs.
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You will visit the study clinic multiple times over 5 years. At your visits, you'll have blood tests and an ultrasound scan of your liver (FibroScan), which is painless and takes about 10 minutes. Researchers may also take a small tissue sample from your liver for laboratory analysis. Throughout the 5-year follow-up period, the study team will monitor your health to understand how the disease develops and which patients are at highest risk for serious liver damage.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
Belgium
Czechia
France
Germany