Plain-English translation of NCT05653778 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing Scrambler Therapy, a non-invasive electrical treatment that sends gentle electrical signals through electrodes placed on your skin to help reduce pain. The therapy works by sending 'non-pain' information along your existing nerve pathways to help your nervous system stop perceiving pain signals so intensely. Early results from a small group of patients with corticobasal syndrome suggest this treatment may provide lasting pain relief.
Pain is a common and serious problem for people with corticobasal syndrome, getting worse as the disease progresses and making it hard to sleep and do daily activities. Currently, there are no good treatment options, so researchers are testing this electrical approach to see if it can offer relief where other pain treatments have fallen short.
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You would receive Scrambler Therapy sessions where small electrodes are placed on your skin over the area where you feel pain. The device sends gentle electrical signals through these electrodes. Researchers will compare your results to those of people receiving standard TENS treatment (a similar but different electrical therapy) to see which works better. Your pain levels will be tracked before treatment, during sessions, and afterward to measure improvement.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
United States