Plain-English translation of NCT05658302 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson Disease research guide →Researchers are studying how deep brain stimulation — a surgical implant that sends electrical signals to specific brain regions — affects Parkinson's disease symptoms and brain function. This trial will enroll about 30 people who are already planning to have this surgery as part of their routine care, and will carefully measure how the device helps with movement problems and thinking.
Deep brain stimulation helps many people with Parkinson's disease, but the results vary widely from person to person, and doctors don't yet fully understand why or how to predict who will benefit most. This study aims to map out the brain circuits involved so that doctors can eventually tailor the treatment to each patient's specific needs and avoid potential cognitive side effects.
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You would undergo brain stimulation surgery at the University of Minnesota, where doctors will implant the device using a special type of lead that allows very precise control. Before and after surgery, you will have detailed brain imaging and testing to help researchers understand how the implant affects your brain circuits and symptoms. The study will track your motor function and cognitive abilities over time to build a better picture of how this treatment works.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
United States
Sponsor
University of Minnesota
Enrollment target
~30 participants
Started
March 2023
Primary completion
March 2027
Age range
21 Years and older
Sex
Female only
Last updated on clinicaltrials.gov in January 2026.
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Central contact
Emily Weatherill
University of Minnesota
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