Brain imaging study to understand tau protein in Alzheimer's disease

This study uses a brain imaging technique with a radiotracer called AV-1451 to measure tau protein, which is a hallmark of Alzheimer's disease. Researchers want to understand how tau levels relate to other markers of brain health in people who are already participating in the larger Mismatch Prospective Cohort study. This imaging data will help scientists better understand how Alzheimer's develops and progresses.

Tau protein accumulation is a key feature of Alzheimer's disease, but researchers don't fully understand how it relates to other signs of brain disease. By measuring tau in study participants who already have detailed health information, scientists hope to unlock new insights that could lead to better diagnosis and treatment of Alzheimer's.