Plain-English translation of NCT05659524 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
After surgery to remove a pituitary tumor through the nose, doctors want to know the best way to care for your nasal passages during healing. This study compares two approaches: some patients will use saline (salt water) nasal rinses twice a day after surgery, while others will follow standard care without the rinses. Researchers will track how well each group recovers and how satisfied patients are with their nasal health.
Endoscopic pituitary surgery is effective, but doctors are still learning the best post-surgery care routine. Previous research helped clarify when antibiotics are needed, and now researchers want to understand whether saline rinses improve healing and comfort during recovery.
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If you enroll, you will be randomly assigned to one of two groups after your pituitary surgery. One group will perform saline nasal rinses twice daily for a period of time after surgery, while the other group will receive standard post-operative care without rinses. You will complete brief questionnaires about your nasal symptoms and healing at follow-up visits, and your surgical team will monitor your recovery as usual.
AI-generated summary from trial data · Jul 3, 2026 · Not medical advice
United States
Sponsor
Lori Wood
Collaborators
Barrow Brain and Spine
Enrollment target
~140 participants
Started
December 2020
Primary completion
December 2028
Age range
19 Years – 85 Years
Last updated on clinicaltrials.gov in April 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Val Calores
Lori Wood
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.