Plain-English translation of NCT05659589 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
When your kidneys suddenly stop working properly (acute kidney injury), harmful substances called uremic toxins can build up in your blood. This study wants to understand whether one of these toxins, called indoxyl sulfate, damages your heart and blood vessels. Researchers will measure this by checking how stiff your arteries are at the time of your injury and again three months later.
Doctors know that people who have acute kidney injury face higher risk of heart and blood vessel problems, but they don't fully understand why. This study aims to figure out whether toxic substances are responsible for this damage—information that could help doctors better protect patients in the future.
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You will have heart and blood vessel tests performed at your hospital bedside or clinic—specifically, a painless measurement of how stiff your arteries are. You'll have these tests done when you enter the study and again at three months after your kidney injury. Blood samples may also be taken to measure the toxin levels. The study takes about three months total.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
France