Plain-English translation of NCT05663151 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing how Prolonged Exposure therapy — a well-established talk therapy for PTSD — works to help people recover from trauma. Researchers will monitor veterans' brain activity, heart rate, and other physical stress responses during 10 therapy sessions to understand exactly what changes in the brain and body as the treatment helps people heal.
While this treatment is known to work, researchers don't fully understand the mechanisms behind why it's so effective. By measuring brain and body changes throughout therapy, this study aims to improve the treatment and help even more people recover from trauma.
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You would attend 10 one-hour therapy sessions over several weeks. During each session, you'll wear a special device that measures your heart rate, skin response, and facial expressions, while researchers also monitor brain activity. You'll also complete detailed assessments before treatment starts, at the midpoint, after all 10 sessions, and again one month later, which include questionnaires, interviews, and exercises where you describe your trauma while your brain and body responses are recorded.
AI-generated summary from trial data · Jun 26, 2026 · Not medical advice
United States