Plain-English translation of NCT05663710 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This is a study testing a new treatment combination for advanced clear cell kidney cancer in patients who have never been treated before. The combination includes (given as an injection), plus two oral medications. The trial wants to see if this three-drug approach is safe and how well it works at shrinking tumors.
Advanced kidney cancer is hard to treat, and doctors are looking for better combination therapies that might work more effectively than current standard treatments. This medication has shown promise in early testing, so researchers want to see if adding it to existing drugs improves outcomes.
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You would receive the injected medication () on a set schedule while also taking two oral medications daily at home. You'll have regular clinic visits for blood tests, imaging scans, and check-ins with your medical team to monitor how you're tolerating the treatment and how your tumors are responding. Some participants will also have biopsies (small tissue samples taken) at specific timepoints to help researchers understand how the treatment is working.
AI-generated summary from trial data · Aug 1, 2026 · Not medical advice
United States