Plain-English translation of NCT05667649 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Alzheimer Disease research guide →Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This study is testing a new treatment called for people with mild to moderate Alzheimer's disease who aren't getting enough relief from current medicines. is made from your own fat tissue — doctors remove a small amount of fat, grow the stem cells in a lab, and then inject them directly into your brain through a small reservoir placed under your scalp. This is an early-stage safety study to see if this treatment is safe and if it might help slow memory loss.
Many people with Alzheimer's don't respond well enough to the medications we have today, and their symptoms continue to get worse. Researchers are exploring whether using a patient's own stem cells might help protect brain cells or slow the disease in ways that current treatments cannot.
First, you'll have a small procedure to place a soft plastic reservoir under your scalp, which sits near the fluid-filled spaces in your brain. Next, doctors will remove a small amount of fat tissue (similar to liposuction), send it to a lab to grow your stem cells, and then inject them into the reservoir through a simple procedure. You'll then be monitored closely for 12 months with visits, brain scans, memory tests, and blood or spinal fluid samples to check for safety and see if the treatment is helping.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
United States
Phase
Safety & dosing
Sponsor
Regeneration Biomedical, Inc.
Enrollment target
~7 participants
Started
August 2023
Primary completion
June 2026
Age range
45 Years – 80 Years
Last updated on clinicaltrials.gov in September 2026.