Plain-English translation of NCT05669534 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether adding extra support and teaching strategies to HIV prevention counseling helps people who use opioids and are taking PrEP (a medication that prevents HIV infection) learn and remember prevention information better. The study will test 16 different combinations of teaching methods—such as more frequent sessions, memory aids, simplified language, and practice planning—to see which approaches work best for helping people stay safe and stick with their prevention plan.
People who inject drugs and are at risk for HIV often struggle to remember and use HIV prevention information, even when they're motivated and taking the right medication. This trial is trying to figure out which teaching methods and support strategies help people actually understand and use what they learn in counseling.
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You will be randomly assigned to receive standard HIV prevention counseling combined with one of 16 different packages of extra support strategies. These might include things like more frequent counseling sessions, memory aids you use between visits, simplified explanations, storytelling techniques to help you prepare for risky situations, or other structured learning methods. Sessions are designed to help you better understand and remember HIV prevention information and develop practical plans to stay safe.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
United States