Plain-English translation of NCT05669703 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Bipolar Disorder research guide →This is a long-term observational study that looks at the relationship between how much you move during the day and how you feel emotionally. Researchers will ask you to wear activity trackers and answer questions about your mood to see if increased physical activity—especially exercise—is connected to better mood states. The study includes people with bipolar disorder, depression, and people without mood disorders, as well as their family members.
Earlier research suggests that increases in movement and exercise may improve mood, particularly for people with bipolar disorder. This study aims to confirm those findings and better understand why this connection exists, which could eventually lead to new ways to help people manage their mood disorders.
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You will wear a small activity tracker to measure your daily movement and complete mood surveys on your phone or tablet multiple times per day over several months. Some participants will also visit the NIH Clinical Center for in-depth assessments including exercise testing, cognitive tests, and other measurements. Family members and spouses of study participants may be asked to join some of these activities as well.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
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