Plain-English translation of NCT05671718 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether nurses working in community clinics can successfully treat drug-resistant tuberculosis (a serious form of TB that doesn't respond to standard medications) just as well as doctors working in hospitals. The study will compare treatment outcomes and costs for patients who receive care close to home in primary care clinics led by trained nurses versus patients who travel to hospital-based clinics led by physicians.
Drug-resistant tuberculosis patients in South Africa are currently required to travel to hospitals for treatment, which costs them significant money and time, and many patients stop coming for care. This trial exists to see if bringing this treatment to neighborhood clinics where nurses provide care can make it more affordable, accessible, and easier for patients to stick with their treatment.
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If you join this trial, you will be randomly assigned to receive your drug-resistant tuberculosis treatment either at a primary care clinic near your home with a nurse visiting once or twice weekly, or at a hospital-based clinic with a physician. You will attend regular clinic visits to take your medication, have blood tests and heart monitoring, and be checked for side effects and treatment progress. The trial will track how quickly you improve, whether you stay with your treatment, and the costs to you and your family compared to the hospital-based approach.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
South Africa