Plain-English translation of NCT05672043 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a research study for children and teenagers (ages 0–18) who have been diagnosed with a malignant brain tumor, including medulloblastoma, glioma, ependymoma, or germ cell tumors. Researchers will collect blood samples and tumor tissue during your surgery and follow your health over time to understand the genetic and molecular characteristics of these tumors and how they affect outcomes.
Brain tumors in children are rare but serious. Doctors currently struggle to predict which patients will respond well to treatment and which may face relapse or complications. By studying the genetic makeup of these tumors, researchers hope to identify patterns that could lead to more personalized treatment plans and better survival rates in the future.
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After your surgery, doctors will collect a sample of your tumor tissue and blood. You will be registered in the study and followed closely: at 3 months, 6 months, 1 year after surgery, and then yearly afterward through clinic visits or phone calls. During these follow-up visits, you will have MRI scans to check for any signs of tumor return, and doctors will evaluate your neurological health and quality of life. Your samples will be sent to a laboratory for genetic testing to help researchers understand your specific tumor.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
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