Plain-English translation of NCT05672615 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is investigating whether BCG (a medication commonly used to treat non-muscle invasive bladder cancer) affects patients' mood, anxiety, or depression. Researchers want to understand the emotional side effects that may occur during and after this standard treatment by collecting information about your mood, along with blood and urine samples.
Doctors know that this medication can cause physical side effects, but there is limited research on how it might affect mental health and mood. By studying these emotional changes, doctors hope to better support patients and develop strategies to manage any mood-related side effects.
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You will visit the clinic regularly over several months as part of your standard cancer care. At each visit, you'll complete brief questionnaires about your mood and anxiety using simple rating scales. You'll also be asked to keep a daily mood diary for 6 weeks during initial treatment and again for 3 weeks during maintenance treatment. The study team will collect blood samples at a few key timepoints and urine samples before and after your treatment — some urine samples may be collected at home.
AI-generated summary from trial data · Jun 30, 2026 · Not medical advice
United States
Johns Hopkins University
Enrollment target
~42 participants
Started
March 2023
Primary completion
March 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in November 2025.
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Central contact
Domani Rodriguez
Johns Hopkins University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.