Recruiting

Teaching relationship skills to prevent HIV among young men

Plain-English translation of NCT05678556 on ClinicalTrials.gov ↗ · Source last updated May 2026 · Translation generated July 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing a program called all2GETHER, which combines online lessons and coaching sessions about relationships, communication, and HIV prevention for young men and transgender individuals who have sex with men. The study wants to see whether learning these skills can help prevent HIV and other sexually transmitted infections. Half of participants will receive the full program, and half will be in a comparison group that has access to standard HIV prevention resources.

Young men who have sex with men face higher rates of HIV and other infections. Research shows that healthy relationship skills—like good communication and conflict resolution—may help reduce these risks, but this hasn't been thoroughly tested in a large study.

Do you qualify?

You likely qualify if…

you are between 16 and 34 years old
you are cisgender male, transgender, or non-binary
you have tested negative for HIV
you have had unprotected anal sex with two or more male partners in the last 6 months (partners whose HIV status was unknown or different from yours)
you have reliable internet access and can read English at an 8th-grade level or higher

You likely don't qualify if…

you were assigned female at birth and identify as a woman
you have tested positive for HIV (though some HIV-positive partners of eligible participants may join in a limited way)
you do not have an address where you can receive test kits by mail

What participation looks like

You'll first complete a baseline assessment with information about your health and relationships. Then you'll be randomly assigned to either the all2GETHER program or a comparison group. If you're in the program and have a partner who enrolls with you, you'll complete three online modules and attend two video coaching sessions together (tailored to your relationship). If you're single or your partner doesn't enroll, you'll use an interactive web app with videos and activities instead. Everyone will be followed for 24 months after the program ends, with periodic check-ins to see how you're doing.

Teaching relationship skills to prevent HIV among young men

What is this trial?

Do you qualify?

What participation looks like

Trial locations(1 site)