Plain-English translation of NCT05679622 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Ulcerative Colitis research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing fecal microbiota transplantation (FMT)—a procedure where stool from a healthy donor is transferred into a child's digestive system—combined with a specialized liquid nutrition plan. Researchers believe that restoring healthy bacteria in the gut may help reduce inflammation and symptoms of ulcerative colitis in children. The study has two main groups: children newly diagnosed with mild-to-moderate ulcerative colitis, and children whose disease hasn't responded well to standard medications.
Ulcerative colitis happens when the gut bacteria become imbalanced and the immune system attacks the intestines. This medication aims to restore healthy bacteria and calm the immune response, potentially offering children relief without relying only on steroids or other strong drugs that can have side effects.
You likely qualify if…
You likely don't qualify if…
You would receive at least one stool transplant procedure, with the option for additional treatments spaced about 2 months apart if needed. At the same time, you would follow a specialized liquid nutrition plan (a polymeric diet) designed to help your gut heal. Throughout the study, you would have regular colonoscopy visits so doctors can monitor how well the treatment is working and check on your intestinal healing. The goal is to help you achieve remission and potentially reduce or stop other medications you may be taking.
AI-generated summary from trial data · Jul 13, 2026 · Not medical advice
China