Plain-English translation of NCT05679739 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
After someone survives cardiac arrest, the brain can be damaged by lack of oxygen and blood flow during and after the event. This study tests whether using special monitoring equipment to measure blood flow in the brain and then adjusting blood pressure to match each person's individual needs can reduce the amount of brain injury that occurs. Researchers will measure brain injury using a blood test that shows how much brain damage has happened.
When the heart stops and is restarted, brain injury is a major cause of disability and death. Currently, doctors use a standard blood pressure target for all patients, but this one-size-fits-all approach may not be optimal. This study explores whether tailoring blood pressure management to each person's individual brain blood flow needs could better protect the brain and improve outcomes.
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You would be admitted to the intensive care unit where doctors would place special monitoring equipment on your head to measure blood flow in your brain using ultrasound and infrared light sensors. Over the first 72 hours after your heart is restarted, doctors would use this information to calculate your personalized blood pressure target and adjust medications to maintain that target. A blood test would be taken at the beginning and at 72 hours to measure brain injury markers.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
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