Plain-English translation of NCT05681702 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Coronary Artery Disease research guide →Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
After you receive a stent to open a blocked heart artery, doctors typically prescribe two blood-thinning medications together to prevent clots. This trial is testing whether you can safely switch to a gentler combination after a few months, or whether staying on the stronger medication alone works better. The goal is to find a way to protect your heart while reducing your risk of serious bleeding.
The stronger blood-thinning medications are very good at preventing clots and stent problems, but they carry a higher risk of dangerous bleeding. Researchers want to know if either switching to a weaker combination or using just one stronger medication can keep you safe from clots while lowering your bleeding risk.
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You will be assigned to take one of two medication combinations: either a gentler two-medication regimen (), or a single stronger medication (). You will continue taking your assigned medication as directed and likely have follow-up visits to monitor how well the treatment is working and check for any side effects or bleeding problems. The study is designed to compare how safely and effectively each approach prevents clots while minimizing bleeding.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
United States