Plain-English translation of NCT05683730 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Crohn's Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether intermittent caloric restriction—eating fewer calories on a regular schedule—can help people with mild to moderate Crohn's disease manage their condition. Crohn's disease is a chronic inflammation of the digestive tract, and diet is known to play a role in how the disease progresses. This study will compare people who follow this eating pattern with people receiving routine care to see if the treatment helps reduce inflammation and improve symptoms.
While doctors know that diet affects Crohn's disease and that controlled eating has helped in other inflammatory conditions, there is no clear agreement on the best way to use nutrition to manage Crohn's disease. This trial is the first to systematically test whether eating fewer calories at set times can improve outcomes for patients.
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You will be randomly assigned to either follow an intermittent caloric restriction plan for 16 weeks or continue your routine care. If you are in the caloric restriction group, you will eat fewer calories on a scheduled basis while receiving support and monitoring. Throughout the study, you will have regular visits where researchers will track your symptoms, disease activity, and how well you tolerate the eating plan using blood tests and symptom questionnaires.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
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