Plain-English translation of NCT05684731 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Ovarian Cancer research guide →Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This study is testing a new treatment approach called , which is a genetically engineered virus designed to infect and kill cancer cells while leaving healthy cells alone. You would receive injected directly into your abdomen, either 3 or 6 times, followed by standard drugs that your doctor chooses. The trial will track how safe the medication is and whether it helps shrink your cancer.
Ovarian cancer that comes back or stops responding to standard treatments is very difficult to treat, and patients need new options. This new treatment combines a virus-based approach that boosts your immune system with , which may work better together than either one alone.
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You would receive injections of the medication directly into your abdomen on a schedule (either 3 doses or 6 doses, given every 3 days). Starting in week 5 or 6, you would begin standard given by your doctor. The entire study lasts about 6 months after your last dose, during which you'll have regular visits to check how you're responding, monitor for side effects, and run blood tests.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
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