Plain-English translation of NCT05685069 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is looking at silent brain injuries—small strokes that appear on brain imaging but don't cause noticeable symptoms. Researchers want to understand how common these injuries are, what causes them, and which treatable conditions (like high blood pressure, irregular heartbeat, or narrowed blood vessels) might be behind them. The goal is to help doctors catch and treat these hidden problems before they lead to a major stroke.
Silent brain injuries are actually quite common—up to three times more frequent than obvious strokes—but doctors don't yet have clear guidelines on how to work them up or what to do about them. This study exists to figure out whether the same thorough testing used for major strokes would help find treatable causes in patients with these silent injuries, which could dramatically improve stroke prevention.
You likely qualify if…
You likely don't qualify if…
You will undergo a standardized set of tests to evaluate your brain and heart health. This includes a detailed brain MRI, three separate 7-day periods of heart rhythm monitoring (ECG), an ultrasound of your heart, and imaging of the blood vessels in your neck and brain. You'll also have blood work and a full assessment of your stroke risk factors. The study is observational, meaning you won't be taking a new medication—instead, doctors are carefully documenting what they find to better understand silent brain injuries and how to treat them.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
France
Switzerland
Sponsor
Insel Gruppe AG, University Hospital Bern
Enrollment target
~230 participants
Started
March 2019
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
16 Years and older
Last updated on clinicaltrials.gov in November 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Urs Fischer, Prof. Dr. med.
Insel Gruppe AG, University Hospital Bern
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.