Plain-English translation of NCT05686434 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a medication called in patients who have had early-stage lung cancer surgically removed and have a specific EGFR gene mutation. The goal is to see if taking this medication every day for three years after surgery can keep the cancer from coming back. This is called adjuvant therapy—treatment given after surgery to reduce the risk of recurrence.
Early-stage lung cancer can sometimes return even after successful surgery, especially in patients with certain genetic markers. Researchers want to know if this medication, which targets the specific EGFR mutation, can lower the risk of recurrence when given as a preventive treatment after surgery.
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You will take one tablet of the medication by mouth once daily for three years. You'll visit the study clinic for safety check-ins at 12 weeks, then every 12 weeks while taking the medication. After you finish the three-year treatment, the study team will follow up with you every 6 months for five years to watch for any signs of cancer recurrence, and then yearly after that. Blood tests and imaging scans may be done at some visits to monitor your health.
AI-generated summary from trial data · Aug 8, 2026 · Not medical advice
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