Plain-English translation of NCT05689281 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether peer support and help with real-life challenges can help trans women in the Deep South start and stay on PrEP, a medication that prevents HIV infection. The study provides culturally informed support from people with lived experience and connects participants with resources to address barriers like housing, food, and healthcare access. The goal is to make HIV prevention more accessible and achievable for trans women in this region.
Trans women face disproportionate risk of HIV infection, but many don't have access to prevention medication or the support they need to start and stick with it. This trial exists to test whether pairing peer navigation—support from someone who understands the community—with practical help addressing life challenges can increase both uptake and long-term adherence to the medication.
You likely qualify if…
You likely don't qualify if…
You would work with a peer navigator—someone from the trans community trained to help with HIV prevention—who will support you in starting the medication and staying on it long-term. You'll attend quarterly (four times per year) visits where you'll complete surveys about your health and experiences, and the team will help connect you with resources for housing, food, healthcare, and other needs that might get in the way. The entire study lasts about a year, and the support is tailored to your specific situation and challenges.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
United States
Sponsor
CrescentCare
Enrollment target
~200 participants
Started
January 2023
Primary completion
July 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Sex
Female only
Last updated on clinicaltrials.gov in March 2023.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Narquis Barak, MS
CrescentCare
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.