Plain-English translation of NCT05691010 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This early-phase trial is testing a faster way to deliver radiation therapy to the pelvis — compressing treatment into one week instead of the typical five weeks — combined with two chemotherapy drugs called and . The study wants to find out whether most patients can complete this shorter treatment schedule without serious problems. The researchers are enrolling 28 people with stage III endometrial cancer who have already had surgery.
Standard treatment for advanced endometrial cancer usually involves five weeks of radiation therapy combined with chemotherapy, which is a long commitment that can be difficult for patients to complete. This trial is exploring whether a much shorter radiation schedule—just one week—might work as well while making treatment more manageable.
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If you enroll, you would receive one week of pelvic radiation therapy combined with two chemotherapy medications ( and ). The exact schedule of visits and treatments will be determined by the study team at Memorial Sloan Kettering Cancer Center. You will need blood tests before starting to ensure your organs can handle the treatment, and the research team will monitor you closely throughout to watch for side effects and make sure you're able to complete the full course.
AI-generated summary from trial data · Jun 27, 2026 · Not medical advice
United States