Plain-English translation of NCT05691868 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Rheumatoid Arthritis research guide →This trial is evaluating the Exactech Vantage Mobile-Bearing Total Ankle System, a surgical device designed to replace a damaged ankle joint. Researchers will follow patients who receive this ankle replacement for up to 10 years after surgery to see how well the device performs and whether it is safe over the long term. The study is recruiting 400 participants from multiple medical centers outside the United States.
Ankle arthritis and joint damage can be severely disabling, affecting a person's ability to walk and move freely. This study exists to make sure the ankle replacement device is safe and effective over many years, helping doctors understand whether it's a good long-term solution for patients with damaged ankle joints.
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If you qualify and enroll, you will receive ankle replacement surgery using the Vantage device. After surgery, you will attend follow-up visits at your study center at regular intervals over the next 10 years so researchers can monitor how your new ankle is functioning and check for any safety concerns. During these visits, your doctor will examine your ankle, ask about your pain and ability to walk, and may perform imaging tests to see how the device is holding up.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
Spain
Switzerland
Sponsor
Exactech
Enrollment target
~400 participants
Started
April 2019
Primary completion
December 2030
Age range
21 Years and older
Last updated on clinicaltrials.gov in February 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Rachael Craig
SWISS ORTHO CENTER Pain Clinic Basel
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.