Plain-English translation of NCT05692024 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Colorectal Cancer research guide →Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This is a research study testing whether Nestlé NESCAFÉ® TASTER'S CHOICE® House Blend coffee in capsule form might help prevent colorectal cancer from coming back after treatment. Coffee contains many natural compounds that early research suggests may help fight cancer, but we don't yet fully understand how it works or if it's truly effective. This study will help answer that question.
Observational studies show that people with colorectal cancer who drink coffee tend to live longer and have better outcomes, but doctors don't yet know why or whether coffee actually causes this benefit. This trial aims to test whether the medication is truly protective and to understand the biological mechanisms behind any benefits.
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You would attend two study visits and take either coffee capsules or placebo capsules by mouth every day for 8–12 weeks (equivalent to about three cups of coffee per day). During your visits, you'll have imaging tests like MRI and ultrasound, provide blood and stool samples, answer questions about your diet and lifestyle, and possibly have a review of your original tumor tissue. The capsules will be mailed to you, and you'll take them at home on your own schedule.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
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