Plain-English translation of NCT05700916 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing milk polar lipids (special fats found in milk) to see if they can improve cholesterol levels and reduce inflammation in adults with high cholesterol and belly fat. Half of the participants will receive a dairy powder containing these milk polar lipids, while the other half will receive a similar-looking dairy powder without them. Over 8 weeks, researchers will measure changes in cholesterol, inflammation markers, and gut health.
Many adults have high cholesterol and excess belly fat, which increase the risk of heart disease. This medication may offer a natural, food-based way to improve cholesterol and reduce inflammation without the side effects of some traditional medications.
You likely qualify if…
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You will be randomly assigned to drink either the special milk powder or a control powder (you won't know which one you're getting) mixed with water or another beverage once daily for 8 weeks. You'll likely have a few clinic visits where researchers will take blood samples, measure your waist, and ask about your health. You may also provide stool samples so they can check your gut bacteria and other markers of health.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
United States
Phase
Safety & dosing
Sponsor
University of Connecticut
Collaborators
Dairy Management Inc.
Enrollment target
~130 participants
Started
October 2023
Primary completion
May 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 70 Years
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Christopher N Blesso, Ph.D.
University of Connecticut
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.