Plain-English translation of NCT05701358 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
After a heart attack, patients often have blockages in more than one artery. This trial tests whether using heart function measurements (called physiology-guided treatment) is safer and works as well as using imaging alone when deciding which extra blockages to treat. The study will follow over 5,000 patients to see which approach prevents future heart problems better.
When patients have multiple blocked arteries, doctors need to decide which ones to treat right away and which ones to monitor. This trial exists to find out whether measuring how much the blockages actually restrict blood flow (the new measurement approach) is better than relying only on what the blockages look like on X-ray images.
If you join this study, you will be randomly assigned to one of two groups. One group will have their extra blockages assessed using heart function measurements before deciding on treatment, while the other group will have all identified blockages treated based on imaging alone. You will receive the necessary heart procedures and then be followed for 5 years with visits and check-ins to monitor your heart health and any complications.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
United States