Plain-English translation of NCT05702229 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing several new experimental medications—including , , and sonesitatug vedotin—combined with standard chemotherapy drugs to treat advanced stomach cancer. The study is divided into four separate groups, each testing a different combination of these medications. Researchers want to see if these new combinations work better than existing treatments and are safe for patients to receive.
Advanced stomach cancer is very difficult to treat, and many patients don't respond well to current standard chemotherapy alone. This trial is exploring whether adding newer, targeted medications to standard chemotherapy can improve how well the treatment works and help patients live longer.
You likely qualify if…
You likely don't qualify if…
You will be assigned to one of four study groups, each testing a different drug combination. Your treatment will include regular infusions or pills of the experimental medication combined with standard chemotherapy drugs, given on a set schedule. You'll have frequent clinic visits for blood tests, imaging scans, and physical exams to monitor how well the treatment is working and watch for side effects. The trial will track your health for several months as the research team evaluates whether this medication helps your cancer and how your body tolerates the treatment.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
United States