Plain-English translation of NCT05702398 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing whether (a form of vitamin B3) and , taken as daily pills, can help prevent skin cancer in kidney transplant recipients who have had skin cancer before. About half of participants will receive the active vitamins, and half will receive placebo pills that look identical but contain no active ingredients. The study will measure whether the medication is safe and whether it affects vitamin levels in the blood.
Kidney transplant recipients have a much higher risk of developing skin cancer compared to the general population. Researchers want to know if this treatment could help prevent future skin cancers in this high-risk group and whether it might be worth testing in larger studies.
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You would take either the vitamin pills or identical placebo pills twice each day. The study involves visits to the research clinic where blood samples will be drawn to measure your vitamin levels and check your overall health. The trial is designed as a preliminary study with a small group of 30 participants to gather safety information and understand how the treatment affects your body before a larger trial might be considered.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
United States
Phase
Safety & dosing
Sponsor
Rhode Island Hospital
Enrollment target
~30 participants
Started
April 2023
Primary completion
January 2028
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2026.
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Central contact
Eunyoung Cho, ScD
Rhode Island Hospital
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