Recruiting

Using Advanced Imaging to Predict Breast Cancer Treatment Response

Plain-English translation of NCT05704062 on ClinicalTrials.gov ↗ · Source last updated April 2026 · Translation generated July 2026 · How we translate trials

What is this trial?

This trial is testing whether advanced MRI scans can better predict how well a patient will respond to chemotherapy for breast cancer. Researchers want to see if these special imaging techniques can identify which patients are responding to treatment earlier and more accurately than traditional tumor size measurements. The study will compare these new imaging methods to standard approaches used today.

Currently, doctors mainly use tumor size measurements to see if chemotherapy is working, but this can take weeks or months to show results. This trial aims to find faster, more accurate ways to predict which patients will benefit from the treatment so doctors can make better decisions about care earlier in the process.

Do you qualify?

You likely qualify if…

you have been diagnosed with breast cancer and are scheduled to receive chemotherapy before surgery
you are able to have an MRI scan without complications (no pacemaker, aneurysm clips, or other metal implants that would interfere)
you have normal kidney function to safely receive the MRI contrast dye through an IV
you are not pregnant
you are able to lie still on an MRI table for about 45 minutes and can understand and sign a consent form

You likely don't qualify if…

you have a pacemaker, aneurysm clip, or other metal implants that would make an MRI unsafe
you have severe claustrophobia or cannot tolerate lying in an MRI machine for 45 minutes
you have kidney problems (low kidney function score)
you are pregnant or breastfeeding
you have a known severe allergic reaction to MRI contrast dye

What participation looks like

If you join this study, you will have four MRI scans: one before starting chemotherapy, one after your first treatment cycle, one at the midpoint of your treatment, and one after you finish chemotherapy. Each scan takes about 45 minutes and uses special imaging techniques to measure how your tumor is responding to treatment. These scans will be compared to your surgery results later to see how accurate the imaging predictions were.

Using Advanced Imaging to Predict Breast Cancer Treatment Response

What is this trial?

Do you qualify?

What participation looks like

Trial locations(4 sites)