Plain-English translation of NCT05705492 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether , a medication that may help stimulate appetite, can help cancer patients gain weight and maintain their strength during treatment. Researchers want to see if this medication works better than a placebo (a dummy pill with no active ingredient) at helping patients with advanced cancers of the stomach, liver, bile ducts, colon, or lungs recover lost weight over 12 weeks.
Cancer and cancer treatments often cause patients to lose their appetite and weight, which can weaken them and make it harder to complete their cancer therapy. This medication has not been thoroughly studied for this specific problem, so researchers are testing whether it could be a helpful new option for patients who are struggling to eat and maintain their weight.
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If you join, you will be randomly assigned to take either a low dose of the medication, a higher dose, or a placebo pill every night for 12 weeks. You'll visit the study team regularly to weigh yourself, answer questions about your appetite and how you're feeling, and have your blood checked. Optional additional tests include CT scans and monthly blood samples. After 12 weeks, you may choose to continue taking the low dose of the medication for another 12 weeks if you wish.
AI-generated summary from trial data · Jul 21, 2026 · Not medical advice
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