Plain-English translation of NCT05706766 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Multiple Myeloma research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
The PROTECT trial is testing whether a supervised exercise program done at home can help people with multiple myeloma prepare their bodies before undergoing an autologous stem cell transplant. You would use a stationary bike and resistance equipment guided by a trainer via tablet for 8 weeks before your transplant. The study wants to see if this preparation helps protect your strength and fitness during and after the transplant.
Stem cell transplants are intense treatments that can weaken the body and make recovery harder. Researchers believe that going into the transplant in better physical condition might help patients stay stronger, recover faster, and have fewer complications afterward.
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If you are randomly assigned to the exercise group, you will do 3 supervised exercise sessions per week for 8 weeks from home using a stationary bike, resistance bands, and a heart-rate monitor guided by a trainer on a tablet. You'll have clinic visits at week 1, week 10, and 30 days after your transplant, along with fitness tests and blood work. The whole study lasts about 4 months. If you're assigned to the comparison group, you'll continue your normal activities and can choose to do the exercise program after the study ends.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
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