Plain-English translation of NCT05706831 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This clinical trial is testing whether a combination of music listening and transcranial electrical stimulation (a non-invasive brain stimulation technique) can help people recover after stroke or improve consciousness in patients with disorders of consciousness. Researchers want to understand how music and electrical stimulation might work together to help the brain heal, and whether this combination reduces stress for family caregivers.
Many stroke patients and people with consciousness disorders have limited treatment options. This trial explores whether music and brain stimulation—non-drug approaches—might unlock the brain's natural healing abilities in ways we don't yet fully understand.
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You will be randomly assigned to one of three groups. Over 4 weeks, you'll listen to music combined with either real or sham (fake) electrical brain stimulation for 2 weeks, take a 1-week break, then receive the opposite treatment for 2 weeks. A neurologist will evaluate your progress, and researchers will measure brain activity before, during, and after treatment. Your caregiver may also be asked about their stress levels and wellbeing throughout the study.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
Italy
Sponsor
Istituti Clinici Scientifici Maugeri SpA
Collaborators
University of Bari Aldo Moro, University of Aarhus
Enrollment target
~90 participants
Started
September 2022
Primary completion
December 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in June 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Simona Spaccavento
Istituti Clinici Scientifici Maugeri SpA
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.