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This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is testing whether a blood test that detects tiny pieces of cancer DNA floating in your bloodstream can help doctors predict whether your head and neck cancer will come back after radiation therapy. Right now, doctors use PET-CT scans to check for leftover cancer, but these scans aren't always accurate—they often show false alarms from inflammation. This study wants to see if the blood test could give doctors a clearer, more reliable answer about whether the cancer has truly responded to treatment.
After radiation treatment for locally advanced head and neck cancer, doctors struggle to know for certain whether all the cancer is gone. Current imaging scans can be misleading, sometimes showing cancer when there isn't any, or missing cancer that's still there. This research aims to find a better, more reliable way to detect leftover cancer so doctors can make smarter decisions about next steps in your care.
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You will undergo your standard chemotherapy and radiation treatment as planned. At specific points during and after your treatment, you will have blood drawn so researchers can test for circulating cancer DNA. You will also have standard imaging scans (PET-CT) to monitor your response. The study team will compare the blood test results with your imaging results to see which method better predicts whether the cancer returns. Follow-up visits will be part of your regular cancer care.
AI-generated summary from trial data · Jul 18, 2026 · Not medical advice
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