Plain-English translation of NCT05711758 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →This pilot study is testing a new procedure called Pylorus Sparing Antral Myotomy (PSAM) to help people with obesity lose weight. The procedure involves using an endoscope—a thin, flexible camera—to make controlled changes to the muscle in your stomach. These changes are designed to slow down how quickly food leaves your stomach, which may help you feel fuller longer and lose weight.
Current weight loss treatments include medications and surgery, but researchers are looking for options that are less invasive than traditional surgery while still being effective. This new treatment is being studied because it may offer a safer, gentler alternative for people struggling with obesity.
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If you are selected, you will undergo an endoscopic procedure where doctors use a thin camera to access your stomach and perform the myotomy treatment. You will also participate in a lifestyle modification program (diet and exercise guidance) as part of your care. You will need to return for follow-up visits to allow researchers to monitor your weight loss, safety, and how well the procedure is working.
AI-generated summary from trial data · Jun 8, 2026 · Not medical advice
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