Combining three treatment approaches to shrink advanced liver cancer

This trial is testing whether combining three different approaches can help patients with advanced liver cancer. The study combines a procedure called transarterial chemoembolization (which delivers chemotherapy directly to the tumor), a targeted medication like lenvatinib or apatinib (which stops cancer cells from growing), and an immune-boosting medication (which helps your body fight cancer). The goal is to shrink the cancer enough that surgery becomes possible.

Many patients with advanced liver cancer cannot have surgery right away because their tumors are too large or spread too far. This trial is testing whether combining three different types of treatment might shrink the cancer enough to make surgery a realistic option later.