Plain-English translation of NCT05719415 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is studying how the smallest blood vessels in your lungs recover after you receive a balloon pulmonary angioplasty—a procedure that opens narrowed lung arteries blocked by blood clots. Researchers want to understand exactly how much of your lung's blood vessel network needs to be restored for the treatment to help you feel better and improve blood flow to your heart.
Right now, doctors know that the balloon procedure can help, but they don't fully understand which patients benefit most or how much of the lung's blood vessel network needs to be opened up. This study will help answer those questions by measuring blood vessel function before and after treatment.
You likely qualify if…
You likely don't qualify if…
You will have a specialized blood test that measures how well your lungs' smallest blood vessels are working—once before your balloon procedure and once after. The test involves injecting a tiny, safe tracer substance and measuring how it moves through your lungs. This helps doctors understand whether the procedure successfully restored your lung's blood vessel function.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
Canada
Sponsor
Jewish General Hospital
Enrollment target
~40 participants
Started
March 2023
Primary completion
January 2028
Age range
18 Years – 75 Years
Last updated on clinicaltrials.gov in September 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
David Langleben, MD
Jewish General Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.